Whenever an e2a email is received and it creates a new record (Standard or Custom Object) as per the e2a Email Rule criteria, it is often useful to send an email notification when it is created. This notification email could be sent to the record owner, any specific user or an external email address. If you want to setup such an alert system so that an email alert is sent whenever a new record is created by e2a, then please proceed as follows. The steps below explain the procedure for setting email alerts on 'Lead', but could be used for any other Object (Standard i.e. Case / Custom), by just replacing 'Lead' with that object.
First, we need to create a new custom field in 'Lead', which will be used to indicate the Lead record creation by e2a
Secondly, we need to configure a Field Assignment Rule in the related 'e2a Email Rule' to populate the created checkbox (New e2a Email) on arrival of an e2a email.
Thirdly, we need to create an Email Alert that will be sent out to the record owner/email address whenever a new record is created.
Now, to send an Email alert, we need to setup a Flow in Salesforce
To get started with setting up the Salesforce Flow needed, follow the instructions below:
Click on the gear icon on the top-right of your screen and select Setup
Locate the quick find on the left side of your screen and type in Flows and Click on the first returned result under Process Automation.

Locate and click on the New Flow button on the right of your screen
Choose the Record-Triggered Flow type from the available options and click on the Create button. This will automatically load the Configure Start pop-up.
In the Object lookup, select Lead
Under the Configure Trigger section, for Trigger the Flow when: select A record is created
Under the Set Entry Conditions section, for the Condition Requirements drop-down, choose All Conditions are Met (AND)
Click in the Field and select $Record > Created by e2a
From the Operator drop-down select Equals
In the Value field, enter True and select {!$GlobalConstant.True}
For the Optimize the Flow for: options, select Actions and Related Records
Click on Done
Click on the plus sign after the Start element
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Search for the Send Email Alert element and choose it to use

In the New Action pop-up, search for the earlier created email alert in the Action lookup and select it

Enter a suitable Label and Description for the element
Under the Set Input Values for the Selected Action section, click in the Record ID field and choose $Record > Record Id

Click on Done
Save and Activate the Flow
Congratulations! You have successfully set up an email alert whenever a new Lead record is created by e2a.
Please contact us at support@ortooapps.com for any questions.